Comparative study of regular insulin adhesion to the walls of glass and plastic serum containers

Introduction:Due to the role of insulin in the control of blood sugar and its widespread use,it is very important to fine-tune the amount of insulin that should reach the patient so that the patient is not exposed to the complications of non-regulation of blood sugar. Research has shown that the choice of solution and serum containers is effective in the patient's access to insulin.Our goal is to compare the degree of insulin adhesion to the walls of glass and plastic containers. Methods:First,3 one-lit glass and plastic containers containing5%dextrose were prepared and300 mu of regular insulin was added to them.2cc albumin and plasma were added to glass and plastic containers No2-3.At time0,sampling was done from the end of the set,then the10cc/min flow was maintained and the sampling was repeated at 30-60min.Insulin concentration in the samples was assessed by insulin test kits and the data were analyzed by various tests. Results:At time 0,50% adhesion was observed in glass containers and75% in plastic containers (P<0.05).At 0-30,there was no significant difference in insulin levels between glass and plastic containers(P>0.05).Mean insulin decreased significantly(P<0.05)in glass containers during 60 min but increased(P>0.05)in plastic containers.In general, during one hour,the trend of changes in mean insulin in containers was significant(P<0.05). Discussion: The highest amount of wall adhesion occurs at time0,which is significantly higher in plastic containers than glass.after one hour,a decrease in insulin content occurs significantly in glass containers,while in plastic containers,the amount of insulin increases slightly. Keywords:Insulin,Serum Container,Albumin,Plasma